ALNY·Alnylam Pharmaceuticals, Inc.

Realized volatility (21d)

109.4% 97th pct

Below its peak

-65.9%

vs 200-day average

-40.7%

Up days (1y)

47%

Alnylam Pharmaceuticals, Inc. is currently running 109.4% annualised volatility over the last 21 sessions. Measured against ALNY's own 13 years of daily returns rather than a market-wide average, that is the 97th percentile — an extreme by its own standards, against a typical reading of 43.3%.

ALNY is trading -65.9% below its running peak. Across 13 full years on file, its median worst-drawdown-in-a-year was -30.8%, and the deepest was -66.9% in 2016. The current drawdown is already deeper than this stock's typical annual low point, which puts it in the part of its range where past recoveries began, and where past declines also continued.

Price sits -40.7% from its 200-day moving average. Against every other day in its history, that gap ranks at the 1st percentile — a narrower gap than it typically runs. Over the past year ALNY closed higher on 47% of sessions, and it is currently 3 sessions into a rising streak.

On November specifically: over 13 years of records, ALNY finished the month higher 11 of 13 times, with a median return of +8.6% and an average of +8.0%. Its strongest month historically has been August at +9.6% on average, its weakest October at -6.7%.

Overnight risk is measurable too: ALNY has opened more than 2% away from the prior close in 240 of 3,266 sessions (7.3% of the time), with the largest gaps running +40.9% and -18.6%.

Across the last 4 dated reports on file, ALNY moved an average of 3.9% in the session after earnings, closing higher 1 of those 4 times, with a median move of -3.2% and a largest of -5.8%.

All figures computed from 3,267 daily closes between 2013-11-06 and 2026-11-05, split-adjusted, recomputed daily. Percentiles are against ALNY's own 13-year history, not a peer group or index.