DailyIQ
Last updated1 minute ago

INSM·Insmed Incorporated

$97.84
+1.05 (+1.08%)
After Hours
High
$98.00
Open
$97.39
Market Cap
21.45B
52W High
$212.77
Low
$95.59
P. Close
$97.84
P/E
-
52W Low
$90.39
Fwd P/E
128.73
DailyIQ Est.
$207.60
Inst. Ownership
47.3%
Short Interest
6.22%
Days to Cover
6.5
Technical Score (1D)
13
BEARISH
News Sentiment
41
BEARISH
INSM is a momentum laggard on the 1D chart: a Technical Score of 13 with declining momentum and weak trend strength. The score ranks stocks against each other, so a reading this low says Insmed Incorporated has been one of the weaker performers in the universe, not that it is oversold. Sentiment at 41 is aligned with that weakness. $100.12 is the level a recovery would need to reclaim, and $90.49 is the next downside reference below $92.42. A bottom momentum rank reflects the prior year of trading, so it changes gradually even when the stock has a strong week. For near-term direction, price levels give the earlier read: a close back above $100.12 on real volume would be the first sign of repair, while a break of $92.42 keeps the bearish trend in charge.
LOW TARGET
$169 +72.8%
2 analysts
MEAN TARGET
$198 +102.8%
8 analysts
HIGH TARGET
$243 +148.5%
22 analysts
PRICE RANGE
$169.00 - $243.00
SB / B / H / S / SS
9/20/1/1/1
DAILYIQ EST.
$207.60 (+112.3%)
Sector
Healthcare
Industry
Biotechnology
Exchange
NMS
Country
United States
Website
Symbol
INSM
Description
Insmed Incorporated is a biopharmaceutical company focused on developing and commercializing therapies for rare and serious diseases. Its core product, ARIKAYCE, addresses refractory nontuberculous mycobacterial lung infections, and the company is advancing a combination therapy for mycobacterium avium complex lung disease. Insmed also has a robust pipeline, including brensocatib, an oral medication in late-stage trials for bronchiectasis, and treprostinil palmitil inhalation powder, currently in phase 3 trials for pulmonary hypertension associated with interstitial lung disease. Furthermore, the company is exploring gene therapy approaches, with a microdystrophin gene replacement therapy in early-stage development for Duchenne muscular dystrophy. Founded in 1988, Insmed is headquartered in Bridgewater, New Jersey, and operates globally.
Bought (1Y)
0 shares
$0
Sold (1Y)
460,952 shares
$57.1M
Brennan David R-
Sell25,000 shares2026-09-09
SHAROKY MELVIN MD-
Sell5,000 shares2026-08-17
Adsett RogerChief Operating Officer
Option Exercise80,970 shares2026-08-10
Adsett RogerChief Operating Officer
Option Exercise76,600 shares2026-08-10
Adsett RogerChief Operating Officer
Option Exercise82,280 shares2026-08-10
45/ 100
Bearish
Overall: Bearish
✓Revenue growing year over year
✕Negative net margin
✕Negative operating cash flow
Gross Margin
79.7%
Net Margin
-210.5%
Revenue CAGR
31.2%
Current Ratio
3.83x
Debt / Equity
0.73x
Return on Equity
-172.8%
Earnings Summary
Insmed Incorporated is a biopharmaceutical company focused on developing and commercializing therapies for rare and serious diseases, with its flagship product ARIKAYCE treating refractory nontuberculous mycobacterial lung infections and a pipeline that includes brensocatib for bronchiectasis and treprostinil palmitil for pulmonary hypertension. In the last two quarters, Q4 2025 revenue of $263.84 million exceeded the $226.34 million estimate, while EPS of –$1.54 fell short of the –$1.1294 estimate, indicating a revenue acceleration but continued earnings loss; Q4 2024 revenue of $104.44 million matched the estimate, but EPS of –$1.32 missed the –$1.16483 estimate, showing a consistent earnings shortfall. Historically, Insmed has posted year‑over‑year revenue growth, with the 2025 quarter beating revenue estimates and maintaining a positive trend, yet EPS has remained negative in each quarter, reflecting ongoing R&D and commercialization costs. Recent news highlights a CFO transition announced on October 5, 2026, coupled with a reaffirmation of 2026 revenue guidance for BRINSUPRI ($1.25–$1.40 billion) and ARIKAYCE ($450–$470 million), suggesting management confidence in the growth narrative despite leadership changes.

EPS

EstBeatMiss
$-1.65$-1.41$-1.17$-0.93$-0.69Q4'24Q4'25Q2'26
QtrEstActual+/−
Q2'26$-0.80 - -
Q4'25$-1.13$-1.54-36.4%
Q4'24$-1.16$-1.32-13.3%

Revenue

EstBeatMiss
$60M$156M$252M$349M$445MQ4'24Q4'25Q2'26
QtrEstActual+/−
Q2'26$400M - -
Q4'25$226M$264M+16.6%
Q4'24 - $104M -

Market Data

INSM Stock Snapshot

BEARISH13/100
$97.79−$0.05 (0.1%)
Market cap
21.45B
Day range
$95.59 – $98.00
News sentiment
41/100 · Neutral
Analyst target
$198.36 (+102.8%)
Consensus
Buy · 32 analysts
52-week range+8.2% off low · -54.0% from high
$90.39$212.77
Price $97.79 DailyIQ Est. $207.60

INSM is on the weaker side of its setup, with little confirmation for a reversal yet. In Healthcare, names this size usually take direction from sector flows before company-level news.

Sector Rotation

Is money rotating into or out of INSM's sector?

Insmed Incorporated sits in the Health Care sector, currently ranked 2nd of 12 GICS sectors by relative-strength rotation score (leading).

Sector rank
#2 of 12
Sector state
Leading
Sector rotation score
82

Options Market

What is the options market pricing for INSM?

CallsPuts

For Insmed Incorporated's nearest expiry (2026-10-16, 2 days out), open interest is call-heavy, a bullish tilt (put/call ratio of 0.25), with at-the-money implied volatility around 66.9%. The options market is pricing roughly a ±6.3% move by that expiry — a range of about $92.92–$105.42.

Put/call ratio (2026-10-16)
0.25
ATM implied volatility
66.9%
Total open interest
3,126
Expected move by 2026-10-16
±6.3% ($92.92–$105.42)

Analyst Rating Changes

Are analysts turning bullish or bearish on INSM?

Wolfe Research most recently downgraded Insmed Incorporated to Peer Perform on Oct 12, 2026. Over the last 90 days, coverage has run 0 upgrades against 1 downgrade, a net bearish lean.

Latest action
Wolfe Research — Peer Perform
90-day upgrades
0
90-day downgrades
1
Net rating momentum
-1
DateFirmActionRatingPrice target
Oct 12, 2026Wolfe ResearchDowngradeOutperform → Peer Perform-
Oct 12, 2026HC Wainwright & Co.ReiteratedBuy$220
Sep 30, 2026BarclaysMaintainedOverweight$237 → $207
Sep 15, 2026Roth CapitalReiteratedBuy$212 → $198
Aug 10, 2026JP MorganMaintainedOverweight$179 → $175
Aug 10, 2026Truist SecuritiesReiteratedBuy$185 → $195
Aug 7, 2026GuggenheimMaintainedBuy$207 → $205
Aug 7, 2026Wells FargoMaintainedOverweight$161 → $169
Aug 7, 2026Evercore ISI GroupMaintainedOutperform$160 → $170
Jul 21, 2026BMO CapitalInitiatedOutperform$192
Jul 15, 2026Wells FargoMaintainedOverweight$160 → $161
Jul 10, 2026GuggenheimReiteratedBuy$207

Peers & ETF holders

INSM peers & ETF holders

News Sentiment Analysis

Sentiment gathered from recent headlines

41/100
Strong NegativeNeutralStrong Positive
BEARISH

Recent News Coverage

Most recent articles, ranked by recency (click to expand).

10+ articles
What did this article say?
Wolfe Research reduced its rating on Insmed from Outperform to Peer Perform on October 12. The downgrade reflects concerns about the company's growth prospects and competitive positioning. The firm cited recent earnings miss and a slowdown in pipeline progress as key factors. This change signals a more cautious view of Insmed’s near‑term outlook.
What did this article say?
Wolfe Research analyst Andy Chen downgraded Insmed (NASDAQ:INSM) from Outperform to Peer Perform on October 12. The downgrade reflects concerns about the company’s recent performance and future outlook. The rating change signals a shift in analyst sentiment toward a more neutral view of Insmed’s prospects.
What did this article say?
On October 12, HC Wainwright & Co. analyst Andrew S. Fein reaffirmed a Buy rating for Insmed (NASDAQ:INSM) and introduced a $220 price target. The upgrade reflects confidence in the company's pipeline progress and revenue outlook. The mandate signals a positive outlook for investors, suggesting potential upside if the company meets its growth expectations. The rating change may influence market sentiment and trading activity around the stock.
What did this article say?
Insmed Inc. (INSM) shares fell nearly 7% on Oct. 6 after the company announced that Chief Financial Officer Sara Bonstein would step down effective Oct. 30. The departure was unexpected, as Bonstein had served for almost seven years and had overseen significant capital raises and the company’s transition to a commercial-stage biotech. Insmed clarified that the exit was unrelated to any accounting or operational disputes and reaffirmed its 2026 revenue guidance, indicating no immediate change to financial outlook. The market reaction reflected investor uncertainty about the leadership transition and its potential impact on future operations.
What did this article say?
Insmed (INSM) delivered a 17.45% annualized return over the past five years, surpassing the broader market by 29.54% per year. The company’s market capitalization reached $22.80 billion as of the latest reporting. This sustained outperformance reflects strong product pipeline execution and robust revenue growth. The data underscores the company’s ability to generate consistent shareholder value. The performance highlights INSM’s competitive positioning in the specialty therapeutics space.
What did this article say?
Insmed Inc announced that Chief Financial Officer Sara Bonstein will step down on October 30, with her remaining in the role until then to ensure a smooth transition. The company is actively searching for a new CFO and stated that the departure is unrelated to any accounting or operational disputes. Despite the leadership change, Insmed’s CEO highlighted a clear path toward cash flow positivity and sustained growth. The announcement caused the stock to fall 8% on the day of the news. The CFO transition may introduce short-term uncertainty but is not expected to materially damage the company’s financial outlook.
What did this article say?
Insmed announced that Chief Financial Officer Sara Bonstein would step down, a move that prompted a modest decline in the company’s shares before the market opened. The resignation was disclosed in a brief statement without additional context regarding succession or operational impact. The news was reported alongside other sector updates, but the focus remained on the leadership change. Investors noted the departure as a potential risk factor, though no immediate operational disruptions were indicated.
What did this article say?
Insmed (INSM) shares fell after the announcement that CFO Sara Bonstein would step down. The company confirmed its 2026 financial targets, maintaining the previously set guidance. The leadership change introduced uncertainty among investors, contributing to the stock’s decline. The reaffirmation of guidance suggests management confidence in future performance, but the CFO exit remains a negative catalyst. The market reaction reflects concerns over potential operational disruptions during the transition.

Technical Analysis

Real-time indicators across multiple timeframes

13
BEARISH
Momentum rank against about 1,000 stocks and ETFs for this timeframe.
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Institutional & Hedge Fund Ownership
25 tracked managers · $12.28B combined position · 14 adding, 11 trimming, 0 unchanged (latest 13F filings)
ManagerTrendShares Held% of Co.Position ValueFiled
Vanguard Group Inc▲ Buy21,076,3449.50%$3.67B2026-01-29
FMR LLC (Fidelity)▲ Buy16,143,5837.28%$1.72B2026-08-13
BlackRock, Inc.▼ Sell15,807,9847.13%$1.69B2026-08-07
JPMorgan Chase & Co▼ Sell10,428,1704.70%$1.09B2026-08-12
D. E. Shaw & Co., Inc.▲ Buy5,877,9592.65%$626.71M2026-08-14
Artisan Partners Limited Partnership▼ Sell5,441,7182.45%$580.20M2026-08-13
Geode Capital Management, LLC▼ Sell4,220,1551.90%$448.76M2026-08-12
Norges Bank▲ Buy3,377,6411.52%$360.12M2026-08-12
Citadel Advisors LLC▲ Buy2,556,9731.15%$272.62M2026-09-02
Maverick Capital Ltd▲ Buy2,150,7620.97%$229.31M2026-08-14
Millennium Management LLC▲ Buy2,048,0050.92%$218.36M2026-08-14
Goldman Sachs Group Inc▲ Buy1,409,8850.64%$150.32M2026-08-14
Balyasny Asset Management L.P.▲ Buy1,326,4300.60%$141.42M2026-08-14
Northern Trust Corp▲ Buy1,315,3250.59%$140.24M2026-08-13
Two Sigma Investments, LP▲ Buy1,242,2220.56%$132.45M2026-08-14
Morgan Stanley▼ Sell1,233,4980.56%$131.52M2026-08-13
Bank of America Corp▼ Sell1,023,1140.46%$109.08M2026-08-14
Adage Capital Partners GP, L.L.C.▼ Sell850,0000.38%$90.63M2026-08-14
Susquehanna International Group, LLP▲ Buy729,3540.33%$77.76M2026-08-14
AllianceBernstein L.P.▼ Sell462,7960.21%$75.68M2026-08-14
Janus Henderson Group plc▼ Sell419,3040.19%$68.56M2026-05-18
William Blair Investment Management, LLC▼ Sell629,8310.28%$67.15M2026-08-12
Squarepoint Ops LLC▲ Buy616,4640.28%$65.73M2026-08-14
AQR Capital Management LLC▼ Sell612,8320.28%$65.33M2026-08-14
Wellington Management Group LLP▲ Buy543,8930.25%$57.99M2026-08-14
Q2 2026 flow:10.34M sh bought ($1.10B)17.10M sh sold ($1.81B)net -6.76M sh (−$707.71M)
Congressional Trading Activity
5 disclosed trades · ~$40.0K est. traded value · 1 buys, 4 sells
MemberChamberStateTypeAmountTradedFiled
Josh GottheimerHouseNJ05▼ Sell$1K - $15K2026-06-102026-07-07
Gilbert CisnerosHouseCA31▼ Sell$1K - $15K2025-08-082025-09-12
Gilbert CisnerosHouseCA31▼ Sell$1K - $15K2025-07-072025-08-14
Josh GottheimerHouseNJ05▲ Buy$1K - $15K2025-06-162025-07-16
Josh GottheimerHouseNJ05▼ Sell$1K - $15K2025-04-092025-05-14