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AZN·Astrazeneca PLC

$158.61
+2.08 (+1.33%)
Pre-Market
High
$159.16
Open
$158.67
Market Cap
184.09B
52W High
$212.82
Low
$158.22
P. Close
$158.61
P/E
23.30
52W Low
$153.41
Fwd P/E
13.71
DailyIQ Est.
$217.59
Inst. Ownership
-
Short Interest
0.18%
Days to Cover
1.0
Technical Score (1D)
14
BEARISH
News Sentiment
66
BULLISH
On Oct 6, Citi raised its price target for AstraZeneca PLC to £186 from £178, citing improved prospects for the tozorakimab drug and higher sales forecasts for other oncology candidates. The brokerage lifted its peak sales estimate for tozorakimab to $7 billion and for SERENA‑6 to $1.1 billion, offsetting the removal of a $1.7 billion forecast for SERENA‑4, and added 4 % to 5 % to the company’s discounted cash flow valuation. On the same day, AstraZeneca announced a $2 billion equity investment in Summit Therapeutics, securing roughly a 12 % stake and aiming to accelerate development of Summit’s lead bispecific antibody, ivonescimab, in combination with antibody‑drug conjugates across multiple tumor types, while Summit retains full development and commercial rights. Also on Oct 6, the company opened a new research and development centre in Cambridge, United States, to broaden its global innovation footprint and support pipeline development and collaboration with local biotech partners. On Oct 5, AstraZeneca disclosed a $1 billion investment in a new Massachusetts R&D centre in Kendall Square, Cambridge, which will house nearly 2,000 scientists and increase the local workforce by more than 50 %, signalling a strategic push to accelerate oncology, cell therapy, chronic disease and rare disease pipelines. That same day, the company announced it would invest more than $1 billion in Massachusetts as part of a $50 billion U.S. expansion plan, further underscoring its commitment to strengthening its U.S. presence and supporting regional talent development.
LOW TARGET
$184 +16.3%
2 analysts
MEAN TARGET
$212 +34.1%
14 analysts
HIGH TARGET
$240 +51.7%
20 analysts
PRICE RANGE
$184.00 - $240.00
SB / B / H / S / SS
13/15/6/1/1
DAILYIQ EST.
$217.59 (+37.5%)
Sector
Healthcare
Industry
Drug Manufacturers - General
Exchange
NMS
Country
United Kingdom
Symbol
AZN
Description
AstraZeneca PLC is a biopharmaceutical company specializing in the research, development, production, and marketing of prescription medications. Its diverse portfolio of products addresses a wide range of therapeutic areas, including oncology, cardiovascular, renal and metabolism, respiratory & immunology, vaccines and immune therapies, and rare diseases. AstraZeneca's commercialization strategy involves distribution and direct engagement with healthcare professionals across key markets like the United Kingdom, the United States, Europe, and Asia. The company strategically partners with other entities, such as Tempus, IonQ, and CSPC Pharmaceutical Group Limited, to advance its research and development initiatives, particularly in oncology and computational chemistry. Originally incorporated in 1992 and headquartered in Cambridge, UK, AstraZeneca has evolved from its prior name, Zeneca Group PLC.
Bought (1Y)
20.233 shares
$3K
Sold (1Y)
0 shares
$0
Sharma ManiSee Remarks
Award/Grant1 shares2026-09-08
Sharma ManiSee Remarks
Buy20.233 shares2026-08-08
Sharma ManiSVP, Group Controller
Award/Grant2 shares2026-08-06
Sharma ManiSee Remarks
Award/Grant2 shares2026-07-06
Sharma ManiSee Remarks
Award/Grant1 shares2026-06-08
Earnings Summary
AstraZeneca PLC is a global biopharmaceutical company focused on research, development, production, and marketing of prescription medicines across oncology, cardiovascular, renal and metabolism, respiratory & immunology, vaccines, and rare diseases, operating in key markets such as the UK, US, Europe, and Asia. The company’s strategy includes partnerships with entities like Tempus, IonQ, and CSPC Pharmaceutical Group to accelerate oncology and computational chemistry research. In the most recent quarters, AstraZeneca’s earnings showed a mixed performance: Q4 2024 EPS of $1.045 beat the $1.03634 estimate while revenue reached $14.891 billion, a slight decline from the prior quarter’s $15.457 billion. Q1 2025 EPS rose to $1.245 against a $1.11569 estimate, with revenue falling to $13.588 billion, reflecting a modest revenue contraction but stronger earnings. Q2 2025 EPS fell to $1.085 versus a $1.46429 estimate, and revenue rebounded to $14.457 billion, indicating a reversal in earnings momentum but a continued upward trend in sales. Q3 2025 EPS of $1.19 beat the $1.13466 estimate, and revenue climbed to $15.191 billion, the highest in the four‑quarter span. Across these quarters, the company has consistently beaten EPS estimates in three of the last four reports, while revenue has trended upward despite occasional quarterly dips. Historically, AstraZeneca has maintained a steady YoY revenue growth trajectory, with EPS growth fluctuating but generally positive, underscoring a resilient top‑line amid competitive pressures. Recent news highlights a $2 billion investment in Summit Therapeutics and the launch of Phase III trials for elecoglipron, an oral GLP‑1 obesity candidate, signaling a strategic push into metabolic therapies and a potential new revenue stream.

EPS

EstBeatMiss
$0.97$1.11$1.25$1.39$1.53Q4'24Q1'25Q2'25Q3'25Q1'26
QtrEstActual+/−
Q1'26$1.22 - -
Q3'25$1.13$1.19+4.9%
Q2'25$1.46$1.08-25.9%
Q1'25$1.12$1.25+11.6%
Q4'24$1.04$1.04+0.8%

Revenue

EstBeatMiss
$13.3B$13.9B$14.5B$15.1B$15.6BQ4'24Q1'25Q2'25Q3'25Q1'26
QtrEstActual+/−
Q1'26$15.4B - -
Q3'25 - $15.2B -
Q2'25 - $14.5B -
Q1'25 - $13.6B -
Q4'24 - $14.9B -

Market Data

AZN Stock Snapshot

BEARISH14/100
$158.66−$0.34 (0.2%)
Market cap
184.09B
P/E ratio
23.3
Day range
$158.22 – $159.16
News sentiment
66/100 · Bullish
Analyst target
$212.17 (+33.7%)
Consensus
Buy · 36 analysts
52-week range+3.4% off low · -25.4% from high
$153.41$212.82
Price $158.66 DailyIQ Est. $217.59

The chart on AZN has not stabilised: price is near its 52-week low and the trend is still down. The stock is liquid enough that positioning changes get absorbed without distorting the trend.

Sector Rotation

Is money rotating into or out of AZN's sector?

Astrazeneca PLC sits in the Health Care sector, currently ranked 3rd of 12 GICS sectors by relative-strength rotation score (lagging).

Sector rank
#3 of 12
Sector state
Lagging
Sector rotation score
36

Options Market

What is the options market pricing for AZN?

CallsPuts

For Astrazeneca PLC's nearest expiry (2026-10-16, 9 days out), open interest is tracked across both sides of the chain, with at-the-money implied volatility around 6.3%. The options market is pricing roughly a ±1.0% move by that expiry — a range of about $162.60–$165.82.

ATM implied volatility
6.3%
Total open interest
15
Expected move by 2026-10-16
±1.0% ($162.60–$165.82)

Analyst Rating Changes

Are analysts turning bullish or bearish on AZN?

CICC most recently initiated coverage on Astrazeneca PLC to Outperform on Aug 24, 2026 with a price target of $198. Over the last 90 days, coverage has run 0 upgrades against 0 downgrades, a net mixed lean.

Latest action
CICC — Outperform
90-day upgrades
0
90-day downgrades
0
Net rating momentum
0
DateFirmActionRatingPrice target
Aug 24, 2026CICCInitiatedOutperform$198
Feb 13, 2025UBSUpgradeNeutral → Buy-
Nov 20, 2024UBSUpgradeSell → Neutral-
Sep 11, 2024Erste GroupUpgradeHold → Buy-
Aug 12, 2024TD CowenMaintainedBuy$90 → $95
May 30, 2024Argus ResearchMaintainedBuy$80 → $85
May 30, 2024Goldman SachsInitiatedBuy$97
Apr 26, 2024BMO CapitalMaintainedOutperform$80 → $82
Apr 16, 2024Deutsche BankUpgradeSell → Hold-
Feb 12, 2024BMO CapitalMaintainedOutperform$82 → $80
Feb 8, 2024Deutsche BankDowngradeBuy → Hold-
Jan 23, 2024Morgan StanleyInitiatedOverweight$85

AZN Competitive Positioning

Astrazeneca PLC (AZN) is tracked alongside these names in Drug Manufacturers - General on DailyIQ — ranked by market cap, with today's move alongside.

News Sentiment Analysis

Sentiment gathered from recent headlines

66/100
Strong NegativeNeutralStrong Positive
MODERATELY BULLISH

Recent News Coverage

Most recent articles, ranked by recency (click to expand).

10+ articles
What did this article say?
AstraZeneca announced a $2 billion investment in US‑listed Summit Therapeutics, a company that licenses its lead cancer drug from China’s Akeso. The deal reflects a broader trend of Western pharma sourcing assets from Chinese biotech as patent expirations create opportunities. Goldman Sachs highlighted that Chinese firms could shorten product cycles for Western drugmakers, potentially benefiting partners like AZN. The investment positions AZN to tap into emerging first‑in‑class therapies and diversify its pipeline. The move is viewed as a positive, though not transformative, development for the company.
What did this article say?
AstraZeneca closed the session at $158.61, outperforming the S&P 500 and Nasdaq. The company’s stock had previously fallen 3.79% before narrowing the gap with the medical sector. Market watchers are awaiting the October 30 earnings release, which is expected to show a 9.24% EPS decline but a 5.82% revenue increase. The consensus estimates project modest full‑year growth of 2.29% in earnings and 7.46% in revenue. The mixed outlook suggests a neutral market reaction.
What did this article say?
Citi lifted its price target for AstraZeneca PLC to £186 from £178, citing improved prospects for the tozorakimab drug and higher sales forecasts for other oncology candidates. The brokerage raised its peak sales estimate for tozorakimab to $7 billion and for SERENA‑6 to $1.1 billion, offsetting the removal of a $1.7 billion forecast for SERENA‑4. The revised outlook added 4% to 5% to AstraZeneca’s discounted cash flow valuation, boosting the target price 9% above the January level. Citi noted that the company’s phase‑3 results across multiple therapies, including Imfinzi and Tagrisso, support a cautiously optimistic view of future growth.
What did this article say?
AstraZeneca announced a $2 billion equity investment in Summit Therapeutics, securing a roughly 12% stake in the company. The deal is intended to accelerate development of Summit’s lead bispecific antibody, ivonescimab, in combination with antibody‑drug conjugates across multiple tumor types. By retaining full development and commercial rights, Summit will continue to lead the program while AstraZeneca gains exposure to a next‑generation cancer therapy that targets both PD‑1 and VEGF pathways.
What did this article say?
AstraZeneca disclosed a $1 billion investment in Massachusetts as part of a broader $50 billion U.S. expansion plan. The announcement came during a broader healthcare sector rally, with the NYSE Healthcare Index rising 0.6% and the XLV ETF adding 0.8%. Despite the sizable capital commitment, AZN shares slipped 0.2% on the day, reflecting a modest market reaction. The investment signals continued growth focus but does not immediately alter the company’s valuation outlook.
What did this article say?
On October 5, AstraZeneca inaugurated a 570,000‑square‑foot research facility in Massachusetts, investing $1 billion to house nearly 2,000 scientists. The new center is expected to increase the company’s local workforce by more than 50 percent. The expansion signals a strategic push to accelerate oncology, cell therapy, chronic disease and rare disease pipelines within a leading life‑sciences ecosystem.
What did this article say?
AstraZeneca (AZN) announced on October 5 that it would invest more than $1 billion in Massachusetts as part of a $50 billion U.S. expansion plan. The capital allocation is intended to grow the company’s local workforce by over 50% in the coming years. The move signals AZN’s commitment to strengthening its U.S. presence and supporting regional talent development.
What did this article say?
On October 5, AstraZeneca announced the opening of a state‑of‑the‑art research and development center in Kendall Square, Cambridge, Massachusetts. The $1 billion investment will expand the company’s Massachusetts workforce by more than 50 percent and house nearly 2,000 world‑class scientists. The facility is positioned at the heart of a leading life‑sciences ecosystem to accelerate the development of oncology, cell therapy, chronic disease and rare disease programs.
What did this article say?
AstraZeneca announced the opening of a new global strategic research and development center in Kendall Square, Cambridge, Massachusetts, investing $1 billion. The investment is expected to increase the company’s Massachusetts workforce by more than 50 percent. The expansion signals a commitment to next‑generation medicine development and positions AZN to accelerate its pipeline in a competitive biotech landscape.

Technical Analysis

Real-time indicators across multiple timeframes

14
BEARISH
Technical indicators reflect the latest computed signal mix for this timeframe.
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Congressional Trading Activity
12 disclosed trades · ~$120.5K est. traded value · 7 buys, 5 sells
MemberChamberStateTypeAmountTradedFiled
Alan ArmstrongSenateOK▲ Buy$1K - $15K2026-03-312026-07-21
Alan ArmstrongSenateOK▲ Buy$15K - $50K2026-03-302026-07-21
Gilbert CisnerosHouseCA31▲ Buy$1K - $15K2025-12-182026-01-12
Lisa McClainHouseMI09▼ Sell$1K - $15K2025-10-312025-11-21
Lisa McClainHouseMI09▼ Sell$1K - $15K2025-10-302025-11-21
Gilbert CisnerosHouseCA31▲ Buy$1K - $15K2025-10-212025-11-18
Valerie HoyleHouseOR04▼ Sell$1K - $15K2025-09-232025-10-10
Lisa McClainHouseMI09▲ Buy$1K - $15K2025-07-222025-08-13
Lisa McClainHouseMI09▼ Sell$1K - $15K2025-06-172025-08-13
Valerie HoyleHouseOR04▲ Buy$1K - $15K2024-10-292025-09-12
Shelley Moore CapitoSenateWV▼ Sell$1K - $15K2019-03-112019-04-17
Shelley Moore CapitoSenateWV▲ Buy$1K - $15K2017-09-082017-10-06