DailyIQ
Last updated1 minute ago

PRAX·Praxis Precision Medicines Inc.

$239.00
-4.34 (-1.78%)
After Hours
High
$245.57
Open
$239.64
Market Cap
6.79B
52W High
$392.70
Low
$236.79
P. Close
$239.00
P/E
-
52W Low
$52.62
Fwd P/E
-26.08
DailyIQ Est.
$741.38
Inst. Ownership
54.3%
Short Interest
15.09%
Days to Cover
7.2
Technical Score (1D)
9
BEARISH
News Sentiment
65
BULLISH
Praxis Precision Medicines Inc. (PRAX) scores 9 on the 1D Technical Score, placing it near the bottom of DailyIQ's momentum ranking: its 12-month price momentum, excluding the latest month, trails most of the stocks we track. The SELL signal and declining momentum reflect that, and the trend bias is bearish. Sentiment at 65 is diverging from the technical read. A low rank describes relative performance, not an oversold condition, so it is not by itself a bounce signal. $261.04 is the first level a recovery would need to clear; $240.96 is the near-term floor. A bottom momentum rank reflects the prior year of trading, so it changes gradually even when the stock has a strong week. For near-term direction, price levels give the earlier read: a close back above $261.04 on real volume would be the first sign of repair, while a break of $240.96 keeps the bearish trend in charge.
LOW TARGET
$188 -21.4%
2 analysts
MEAN TARGET
$644 +169.6%
8 analysts
HIGH TARGET
$1201 +402.5%
16 analysts
PRICE RANGE
$188.00 - $1201.00
SB / B / H / S / SS
9/13/2/1/1
DAILYIQ EST.
$741.38 (+210.2%)
Bought (1Y)
0 shares
$0
Sold (1Y)
11,600 shares
$3.6M
Souza MarcioChief Executive Officer
Gift2,600 shares2026-07-08
Souza MarcioChief Executive Officer
Gift20,521 shares2026-07-08
DeSimone Jill-
Option Exercise3,034 shares2026-06-24
DeSimone Jill-
Option Exercise8,566 shares2026-06-24
DeSimone Jill-
Sell837 shares2026-06-24
39/ 100
Bearish
Overall: Bearish
✕Revenue declining year over year
✕Negative operating cash flow
✓Manageable liabilities relative to assets
Current Ratio
10.22x
Return on Equity
-34.5%

EPS

EstBeatMiss
$-3.67$-3.58$-3.50$-3.41$-3.32Q3'25Q3'26
QtrEstActual+/−
Q3'26$-3.63 - -
Q3'25$-3.49$-3.36+3.7%

Revenue

EstBeatMiss
$-0.15$-0.075$0$0.075$0.15Q3'25Q3'26
QtrEstActual+/−
Q3'26$0 - -
Q3'25 - $0 -

Market Data

PRAX Stock Snapshot

BEARISH9/100
$243.57+$4.57 (1.9%)
Market cap
6.79B
Day range
$236.79 – $245.57
News sentiment
65/100 · Bullish
Analyst target
$644.42 (+164.6%)
Consensus
Buy · 26 analysts
52-week range+362.9% off low · -38.0% from high
$52.62$392.70
Price $243.57 DailyIQ Est. $741.38

Price action on PRAX is defensive - rallies are being sold rather than extended. At this size, a single catalyst moves the stock further than it would a larger peer.

Sector Rotation

Is money rotating into or out of PRAX's sector?

Praxis Precision Medicines Inc. sits in the Health Care sector, currently ranked 2nd of 12 GICS sectors by relative-strength rotation score (leading). Within its narrower Biotechnology industry group, PRAX ranks 9th of 15 tracked industries, improving.

Sector rank
#2 of 12
Sector state
Leading
Sector rotation score
82
Industry rank
#9 of 15

Options Market

What is the options market pricing for PRAX?

CallsPuts

For Praxis Precision Medicines Inc.'s nearest expiry (2026-10-16, 2 days out), open interest is call-heavy, a bullish tilt (put/call ratio of 0.63), with at-the-money implied volatility around 112.8%. The options market is pricing roughly a ±7.3% move by that expiry — a range of about $232.98–$269.78.

Put/call ratio (2026-10-16)
0.63
ATM implied volatility
112.8%
Total open interest
334
Expected move by 2026-10-16
±7.3% ($232.98–$269.78)

Analyst Rating Changes

Are analysts turning bullish or bearish on PRAX?

HC Wainwright & Co. most recently reiterated its rating on Praxis Precision Medicines Inc. to Buy on Oct 6, 2026 with a price target of $1201. Over the last 90 days, coverage has run 0 upgrades against 0 downgrades, a net mixed lean.

Latest action
HC Wainwright & Co. — Buy
90-day upgrades
0
90-day downgrades
0
Net rating momentum
0
DateFirmActionRatingPrice target
Oct 6, 2026HC Wainwright & Co.ReiteratedBuy$1201
Oct 6, 2026BTIGMaintainedBuy$810 → $826
Sep 24, 2026HC Wainwright & Co.ReiteratedBuy$1201
Sep 24, 2026NeedhamReiteratedBuy$582
Aug 21, 2026Goldman SachsMaintainedBuy$470 → $575
Aug 7, 2026RBC CapitalMaintainedOutperform$449 → $462
Aug 7, 2026Wells FargoMaintainedEqual-Weight$323 → $362
Aug 6, 2026NeedhamMaintainedBuy$575 → $582
Jul 29, 2026BTIGReiteratedBuy$810
Jul 13, 2026Goldman SachsInitiatedBuy$447
Jun 29, 2026NeedhamMaintainedBuy$537 → $575
Jun 18, 2026RBC CapitalInitiatedOutperform$449

ETF holders

ETFs holding PRAX

News Sentiment Analysis

Sentiment gathered from recent headlines

65/100
Strong NegativeNeutralStrong Positive
MODERATELY BULLISH

Recent News Coverage

Most recent articles, ranked by recency (click to expand).

10+ articles
What did this article say?
HC Wainwright & Co. analyst Douglas Tsao reiterated a Buy recommendation for Praxis Precision Medicine (PRAX) on October 6. The firm maintained its $1,201 price target, indicating confidence in the company’s growth prospects. The endorsement reflects a positive view of PRAX’s strategic positioning and potential to capitalize on emerging precision medicine opportunities. No immediate catalysts were cited, but the rating supports a bullish outlook for the stock.
What did this article say?
BTIG analyst Kambiz Yazdi maintained a Buy rating on Praxis Precision Medicine (PRAX) and raised the price target from $810 to $826. The upgrade reflects confidence in the company’s pipeline and recent clinical milestones. The new target suggests a potential upside for investors, though it is not a transformative catalyst.
What did this article say?
Praxis Precision Medicine (PRAX) released its second‑quarter 2026 financial results and hosted an earnings call on October 5. The company provided a transcript of the call, outlining its financial performance and strategic priorities. No significant deviations from guidance or material events were disclosed during the session. The announcement serves as a routine update for investors and analysts.
What did this article say?
Praxis Precision Medicines, Inc. (PRAX) announced on October 1, 2026 that its Compensation Committee granted restricted stock unit awards covering 3,478 shares to fourteen new non‑executive employees. The awards are part of the company’s 2024 Inducement Plan and are intended to attract and retain talent. The announcement was issued via a Globe Newswire release and does not indicate any immediate financial or strategic impact on the company.
What did this article say?
Needham analyst Ami Fadia reaffirmed a Buy rating for Praxis Precision Medicine (PRAX) on September 24, maintaining the $582 price target. The upgrade signals confidence in the company’s growth prospects and product pipeline. The recommendation reflects a positive outlook on PRAX’s market positioning and potential upside, though it is not deemed transformative.
What did this article say?
Praxis Precision Medicines (PRAX) has experienced a more than 1,000% share price increase since April 2025, driven by landmark clinical results for ulixacaltamide and relutrigine. Both compounds have achieved statistically significant outcomes and are slated for 2026/2027 PDUFA dates, targeting large CNS markets with combined peak sales potential exceeding $15 billion. The company’s $1.4 billion cash reserve supports a robust commercial buildout, reduces near‑term capital risk, and leaves room for potential out‑licensing and priority review vouchers, sustaining upside expectations.

Technical Analysis

Real-time indicators across multiple timeframes

9
BEARISH
Momentum rank against about 1,000 stocks and ETFs for this timeframe.
Unlock full technicals
Create a free account to access more indicators and deeper timeframe data.
Institutional & Hedge Fund Ownership
25 tracked managers · $4.94B combined position · 18 adding, 7 trimming, 0 unchanged (latest 13F filings)
ManagerTrendShares Held% of Co.Position ValueFiled
Janus Henderson Group plc▲ Buy3,458,86312.46%$1.11B2026-05-18
FMR LLC (Fidelity)▲ Buy2,316,9078.35%$775.68M2026-08-13
BlackRock, Inc.▼ Sell2,292,5858.26%$767.53M2026-08-07
Vanguard Group Inc▲ Buy1,460,9335.26%$430.60M2026-01-29
Adage Capital Partners GP, L.L.C.▲ Buy1,015,4803.66%$339.97M2026-08-14
Morgan Stanley▲ Buy854,1123.08%$285.95M2026-08-13
Geode Capital Management, LLC▲ Buy748,0392.69%$250.48M2026-08-12
Goldman Sachs Group Inc▼ Sell548,8301.98%$183.74M2026-08-14
Bank of America Corp▲ Buy546,9301.97%$183.11M2026-08-14
Invesco Ltd.▲ Buy537,5481.94%$179.97M2026-08-14
Norges Bank▲ Buy346,9691.25%$116.16M2026-08-12
Northern Trust Corp▲ Buy240,8870.87%$80.65M2026-08-13
Marshall Wace, LLP▲ Buy137,0080.49%$45.87M2026-08-13
Wellington Management Group LLP▼ Sell125,8670.45%$42.14M2026-08-14
Neuberger Berman Group LLC▲ Buy89,4680.32%$29.95M2026-08-13
AllianceBernstein L.P.▲ Buy71,5180.26%$23.04M2026-08-14
AQR Capital Management LLC▼ Sell58,4460.21%$19.57M2026-08-14
JPMorgan Chase & Co▼ Sell44,0850.16%$15.81M2026-08-12
Squarepoint Ops LLC▲ Buy42,5010.15%$14.23M2026-08-14
Wells Fargo & Company▲ Buy27,8890.10%$9.34M2026-08-14
Citigroup Inc▲ Buy23,5990.09%$7.90M2026-08-03
Man Group plc▲ Buy21,1640.08%$7.09M2026-08-14
Prudential Financial Inc▼ Sell19,5410.07%$6.54M2026-08-12
Two Sigma Investments, LP▲ Buy18,7580.07%$6.28M2026-08-14
Citadel Advisors LLC▼ Sell7,3310.03%$2.45M2026-09-02
Q2 2026 flow:1.61M sh bought ($538.65M)317.6K sh sold ($107.18M)net +1.29M sh (+$431.47M)
Congressional Trading Activity
2 disclosed trades · ~$16.0K est. traded value · 2 buys, 0 sells
MemberChamberStateTypeAmountTradedFiled
Gilbert CisnerosHouseCA31▲ Buy$1K - $15K2026-09-292026-10-12
Gilbert CisnerosHouseCA31▲ Buy$1K - $15K2026-07-302026-09-04