KYMR·Kymera Therapeutics Inc.

Realized volatility (21d)

39.0% 8th pct

Below its peak

-12.9%

vs 200-day average

+20.1%

Up days (1y)

52%

Kymera Therapeutics Inc. is currently running 39.0% annualised volatility over the last 21 sessions. Measured against KYMR's own 6 years of daily returns rather than a market-wide average, that is the 8th percentile — unusually subdued by its own history, against a typical reading of 64.8%. The distinction matters because a number that looks calm for one stock is turbulent for another, and the absolute figure on its own tells you neither.

KYMR is trading -12.9% below its running peak. Across 5 full years on file, its median worst-drawdown-in-a-year was -63.6%, and the deepest was -78.7% in 2022. The current pullback is therefore shallower than what this stock gives back in a typical year, which is context worth having before treating it as a dislocation.

Price sits +20.1% from its 200-day moving average. Against every other day in its history, that gap ranks at the 64th percentile — a somewhat wider gap than its own norm. Over the past year KYMR closed higher on 52% of sessions, and it is currently 3 sessions into a rising streak.

On October specifically: over 6 years of records, KYMR finished the month higher 3 of 6 times, with a median return of +6.1% and an average of +10.8%. Its strongest month historically has been November at +18.0% on average, its weakest May at -11.6%. Seasonality is a weak signal on its own — a decade is a small sample and regimes change — but it is a real distribution rather than a rule of thumb.

Overnight risk is measurable too: KYMR has opened more than 2% away from the prior close in 262 of 1,540 sessions (17.0% of the time), with the largest gaps running +23.0% and -12.1%. For anyone holding through an event, that rate is a better guide to overnight exposure than the intraday range.

All figures computed from 1,541 daily closes between 2020-08-21 and 2026-10-09, split-adjusted, recomputed daily. Percentiles are against KYMR's own 6-year history, not a peer group or index.