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CYTK·Cytokinetics Incorporated

$63.44
+1.82 (+2.95%)
After Hours
High
$64.01
Open
$61.62
Market Cap
8.64B
52W High
$93.51
Low
$60.99
P. Close
$63.44
P/E
-
52W Low
$54.30
Fwd P/E
-13.86
DailyIQ Est.
$116.80
Inst. Ownership
53.3%
Short Interest
13.88%
Days to Cover
8.4
Technical Score (1D)
27
BEARISH
News Sentiment
53
MIXED
On Oct 13, Cytokinetics presented Phase 3 ACACIA‑HCM data at the 2026 HFSA meeting, showing that more than half of patients treated with aficamten achieved clinical responses in at least three BEAP‑RS domains, compared with just over one‑tenth on placebo. The presentation also highlighted improved global exercise performance in adults with non‑obstructive hypertrophic cardiomyopathy, a finding that could support an expanded label for MYQORZO beyond obstructive disease. On Oct 13, a separate filing revealed that Cytokinetics CEO Robert I. Blum sold 7,500 shares of CYTK for $471,600, reducing his direct holdings to 278,544 shares. The transaction was reported in a Form 4 filed with the SEC on Oct 12, 2026, and lowered his total control to 282,710 shares. The insider sale may signal a shift in confidence or a need for liquidity, potentially influencing investor perception of the company’s prospects.
LOW TARGET
$85 +34.0%
2 analysts
MEAN TARGET
$110 +73.3%
10 analysts
HIGH TARGET
$146 +130.2%
18 analysts
PRICE RANGE
$85.00 - $146.00
SB / B / H / S / SS
6/19/3/1/1
DAILYIQ EST.
$116.80 (+84.1%)
Bought (1Y)
0 shares
$0
Sold (1Y)
312,835 shares
$23.3M
Blum Robert IPresident & CEO
Option Exercise7,500 shares2026-10-12
Blum Robert IPresident & CEO
Sell7,500 shares2026-10-12
Blum Robert IPresident & CEO
Option Exercise7,500 shares2026-10-12
Malik Fady IbrahamEVP Research & Development
Option Exercise3,500 shares2026-10-06
Malik Fady IbrahamEVP Research & Development
Sell3,500 shares2026-10-06
40/ 100
Bearish
Overall: Bearish
✓Revenue growing year over year
✕Negative net margin
✕Negative operating cash flow
Net Margin
-891.6%
Revenue CAGR
0.5%
Current Ratio
4.53x
Debt / Equity
-0.44x
Return on Equity
119.0%

EPS

EstBeatMiss
$-1.59$-1.54$-1.50$-1.45$-1.41Q3'25Q3'26
QtrEstActual+/−
Q3'26$-1.43 - -
Q3'25$-1.57$-1.54+1.6%

Revenue

EstBeatMiss
$-4M$9M$21M$34M$46MQ3'25Q3'26
QtrEstActual+/−
Q3'26$41M - -
Q3'25 - $2M -

Market Data

CYTK Stock Snapshot

BEARISH27/100
$63.43−$0.01 (0.0%)
Market cap
8.64B
Day range
$60.99 – $64.01
News sentiment
53/100 · Neutral
Analyst target
$109.95 (+73.3%)
Consensus
Buy · 30 analysts
52-week range+16.8% off low · -32.2% from high
$54.30$93.51
Price $63.43 DailyIQ Est. $116.80

The trend on CYTK is bearish, and its momentum ranks in the lower part of DailyIQ's universe. At this size, a single catalyst moves the stock further than it would a larger peer.

Behaviour On Record

What CYTK's own history says about today's numbers

Realized volatility (21d)
30.2% 4th pct
Below its peak
-29.4%
vs 200-day average
-12.1%
Up days (1y)
47%

Cytokinetics Incorporated is currently running 30.2% annualised volatility over the last 21 sessions. Measured against CYTK's own 13 years of daily returns rather than a market-wide average, that is the 4th percentile — unusually subdued by its own history, against a typical reading of 52.9%. The distinction matters because a number that looks calm for one stock is turbulent for another, and the absolute figure on its own tells you neither.

CYTK is trading -29.4% below its running peak. Across 12 full years on file, its median worst-drawdown-in-a-year was -41.6%, and the deepest was -76.8% in 2014. The current pullback is therefore shallower than what this stock gives back in a typical year, which is context worth having before treating it as a dislocation.

Price sits -12.1% from its 200-day moving average. Against every other day in its history, that gap ranks at the 22nd percentile — a narrower gap than it typically runs. Over the past year CYTK closed higher on 47% of sessions, and it is currently 2 sessions into a falling streak.

On October specifically: over 13 years of records, CYTK finished the month higher 6 of 13 times, with a median return of -3.1% and an average of -1.7%. Its strongest month historically has been December at +9.9% on average, its weakest September at -4.1%. Seasonality is a weak signal on its own — a decade is a small sample and regimes change — but it is a real distribution rather than a rule of thumb.

Overnight risk is measurable too: CYTK has opened more than 2% away from the prior close in 413 of 3,224 sessions (12.8% of the time), with the largest gaps running +21.6% and -32.4%. For anyone holding through an event, that rate is a better guide to overnight exposure than the intraday range.

All figures computed from 3,226 daily closes between 2013-10-15 and 2026-10-13, split-adjusted, recomputed daily. Percentiles are against CYTK's own 13-year history, not a peer group or index.

Sector Rotation

Is money rotating into or out of CYTK's sector?

Cytokinetics Incorporated sits in the Health Care sector, currently ranked 2nd of 12 GICS sectors by relative-strength rotation score (leading). Within its narrower Biotechnology industry group, CYTK ranks 9th of 15 tracked industries, improving.

Sector rank
#2 of 12
Sector state
Leading
Sector rotation score
82
Industry rank
#9 of 15

Options Market

What is the options market pricing for CYTK?

CallsPuts

For Cytokinetics Incorporated's nearest expiry (2026-10-16, 2 days out), open interest is call-heavy, a bullish tilt (put/call ratio of 0.85), with at-the-money implied volatility around 128.4%. The options market is pricing roughly a ±7.5% move by that expiry — a range of about $57.53–$66.85.

Put/call ratio (2026-10-16)
0.85
ATM implied volatility
128.4%
Total open interest
3,888
Expected move by 2026-10-16
±7.5% ($57.53–$66.85)

Analyst Rating Changes

Are analysts turning bullish or bearish on CYTK?

RBC Capital most recently reiterated its rating on Cytokinetics Incorporated to Outperform on Oct 8, 2026 with a price target of $113 (from $112). Over the last 90 days, coverage has run 0 upgrades against 0 downgrades, a net mixed lean.

Latest action
RBC Capital — Outperform
90-day upgrades
0
90-day downgrades
0
Net rating momentum
0
DateFirmActionRatingPrice target
Oct 8, 2026RBC CapitalMaintainedOutperform$112 → $113
Aug 31, 2026HC Wainwright & Co.ReiteratedBuy$140
Aug 13, 2026BarclaysMaintainedOverweight$95 → $110
Aug 13, 2026JP MorganMaintainedOverweight$97 → $103
Aug 10, 2026Truist SecuritiesMaintainedBuy$106 → $112
Aug 7, 2026RBC CapitalMaintainedOutperform$117 → $112
Aug 7, 2026CitizensMaintainedMarket Outperform$105 → $110
Aug 7, 2026NeedhamMaintainedBuy$102 → $112
Jul 7, 2026RBC CapitalMaintainedOutperform$119 → $117
Jun 29, 2026UBSUpgradeNeutral → Buy$69 → $115
Jun 24, 2026MizuhoMaintainedOutperform$100 → $118
Jun 17, 2026NeedhamReiteratedBuy$102

ETF holders

ETFs holding CYTK

News Sentiment Analysis

Sentiment gathered from recent headlines

53/100
Strong NegativeNeutralStrong Positive
MIXED

Recent News Coverage

Most recent articles, ranked by recency (click to expand).

10+ articles
What did this article say?
On October 12, 2026, Cytokinetics CEO Robert I. Blum sold 7,500 shares of CYTK for $471,600, decreasing his direct ownership to 278,544 shares. The transaction was filed as a Form 4 with the SEC and reduced his total control to 282,710 shares. The sale may signal a shift in insider confidence or a need for liquidity, potentially impacting investor perception of the company’s prospects.
What did this article say?
Cytokinetics presented Phase 3 ACACIA-HCM results at the 2026 HFSA meeting, showing aficamten improved global exercise performance in adults with non‑obstructive hypertrophic cardiomyopathy. Over half of treated patients achieved clinical response in at least three BEAP‑RS domains, compared with just over one‑tenth on placebo. The data support a potential label expansion of MYQORZO beyond obstructive disease, positioning aficamten as a stronger therapeutic option in non‑obstructive HCM. The company’s next catalyst remains the planned Q4 2026 sNDA filing, which could confirm regulatory approval and drive further upside.
What did this article say?
The article discusses the recent increased interest in Cytokinetics (CYTK) without providing specific details or new developments.
What did this article say?
RBC increased its price target for Cytokinetics from $112 to $113 and kept its outperform rating. The upgrade reflects confidence in the company’s pipeline and recent clinical progress. The modest lift signals a slight bullish outlook but does not indicate a major shift in valuation. The move is expected to influence short‑term investor sentiment without materially altering the company’s long‑term prospects.
What did this article say?
RBC Capital analyst Leonid Timashev maintained an Outperform rating for Cytokinetics (NASDAQ:CYTK) and increased the price target from $112 to $113. The upgrade signals confidence in the company’s prospects and suggests a modest upside for investors. The change reflects the firm’s assessment of Cytokinetics’ pipeline and market positioning.
What did this article say?
Cytokinetics, Inc. (CYTK) announced that it would deliver four presentations at the Heart Failure Society of America Annual Scientific Meeting 2026 in Phoenix, Arizona. The schedule includes two late‑breaking clinical research presentations and two oral presentations focused on the global efficacy and exercise performance of its drug aficamten in non‑obstructive hypertrophic cardiomyopathy. The presentations are slated for October 12, 2026, during the HFSA plenary session. The announcement provides a timetable for the company’s upcoming scientific disclosures but does not report any new data or results. The event is a routine part of CYTK’s clinical communication strategy and is unlikely to materially alter investor expectations at this time.
What did this article say?
Cytokinetics (CYTK) announced the initiation of a real‑world study to assess Myqorzo in adults with symptomatic obstructive hypertrophic cardiomyopathy. The trial will enroll roughly 400 patients across 13 cardiology practices and HCM centers over a period of 12 to 36 months. Researchers will monitor safety, efficacy, symptom improvement, and patient‑reported outcomes, as well as hospitalizations, procedures, and healthcare costs. The study aims to determine whether Myqorzo can reduce invasive procedures and improve clinical management in routine practice.
What did this article say?
Cytokinetics, Inc. (CYTK) began the ASPEN‑HCM study on September 30, 2026, to evaluate the safety, effectiveness, and healthcare resource impact of its drug MYQORZO (aficamten) in patients with symptomatic obstructive hypertrophic cardiomyopathy. The multicenter, prospective, observational trial will collect real‑world data from routine clinical practice across several sites. The study aims to provide additional evidence on MYQORZO’s clinical profile and potential value in managing obstructive HCM.
What did this article say?
Cytokinetics announced the initiation of the ASPEN-HCM clinical trial, which will evaluate the efficacy and safety of MYQORZO, an oral myosin inhibitor, in adults with symptomatic obstructive hypertrophic cardiomyopathy. The study aims to determine whether MYQORZO can reduce left ventricular outflow tract gradients and improve symptoms in this patient population. The trial represents a significant step toward advancing CYTK’s pipeline and could broaden the therapeutic options for a rare cardiac condition.
What did this article say?
On September 28, 2026, Cytokinetics CEO Robert I. Blum sold 7,500 shares of the company, amounting to $490,950, as disclosed in a Form 4 filing. The transaction reduced his direct holdings to 278,544 shares, while his total control remained at 282,710 shares. The sale did not trigger any regulatory concerns and was not accompanied by a change in company strategy or guidance. Investors may view the move as a normal portfolio adjustment rather than a signal of impending corporate change.

Technical Analysis

Real-time indicators across multiple timeframes

27
BEARISH
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Institutional & Hedge Fund Ownership
25 tracked managers · $5.92B combined position · 18 adding, 7 trimming, 0 unchanged (latest 13F filings)
ManagerTrendShares Held% of Co.Position ValueFiled
BlackRock, Inc.▲ Buy20,094,36214.42%$1.71B2026-08-07
Vanguard Group Inc▲ Buy12,048,1318.65%$765.54M2026-01-29
Wellington Management Group LLP▼ Sell6,931,7704.98%$590.52M2026-08-14
FMR LLC (Fidelity)▼ Sell5,031,7823.61%$428.66M2026-08-13
Bank of America Corp▲ Buy4,635,7093.33%$394.92M2026-08-14
Geode Capital Management, LLC▲ Buy3,712,5012.67%$316.33M2026-08-12
Goldman Sachs Group Inc▼ Sell1,761,5881.26%$150.07M2026-08-14
Capital Research Global Investors▲ Buy1,686,6251.21%$143.68M2026-08-12
Northern Trust Corp▲ Buy1,647,3451.18%$140.34M2026-08-13
JPMorgan Chase & Co▲ Buy1,588,8951.14%$139.15M2026-08-12
William Blair Investment Management, LLC▲ Buy1,603,4421.15%$136.60M2026-08-12
Point72 Asset Management, L.P.▲ Buy1,587,7121.14%$135.26M2026-08-14
Susquehanna International Group, LLP▲ Buy1,549,4581.11%$132.00M2026-08-14
Morgan Stanley▲ Buy1,510,3181.08%$128.66M2026-08-13
Invesco Ltd.▲ Buy1,235,3230.89%$105.24M2026-08-14
D. E. Shaw & Co., Inc.▲ Buy1,048,1030.75%$89.29M2026-08-14
Norges Bank▲ Buy1,015,5220.73%$86.51M2026-08-12
Fisher Asset Management, LLC▼ Sell743,6970.53%$63.36M2026-08-04
Balyasny Asset Management L.P.▼ Sell711,6760.51%$60.63M2026-08-14
Citadel Advisors LLC▼ Sell640,9450.46%$54.60M2026-09-02
Marshall Wace, LLP▼ Sell451,4670.32%$38.46M2026-08-13
AllianceBernstein L.P.▲ Buy535,9930.38%$35.33M2026-08-14
Citigroup Inc▲ Buy322,9320.23%$27.51M2026-08-03
Two Sigma Investments, LP▲ Buy317,4110.23%$27.04M2026-08-14
ExodusPoint Capital Management, LP▲ Buy249,2590.18%$21.23M2026-08-14
Q2 2026 flow:11.17M sh bought ($952.04M)8.18M sh sold ($697.09M)net +2.99M sh (+$254.96M)
Congressional Trading Activity
2 disclosed trades · ~$16.0K est. traded value · 2 buys, 0 sells
MemberChamberStateTypeAmountTradedFiled
Gilbert CisnerosHouseCA31▲ Buy$1K - $15K2026-09-292026-10-12
Lisa McClainHouseMI09▲ Buy$1K - $15K2025-06-112025-08-13