DailyIQ
Last updated3 minutes ago

RVMD·Revolution Medicines, Inc.

$190.96
-6.01 (-3.05%)
Market Closed (Overnight)$190.52-0.44 (-0.23%)
High
$197.12
Open
$197.12
Market Cap
40.93B
52W High
$225.01
Low
$188.18
P. Close
$190.96
P/E
-
52W Low
$41.70
Fwd P/E
-32.08
DailyIQ Est.
$268.06
Inst. Ownership
69.8%
Short Interest
4.53%
Days to Cover
4.7
Technical Score (1D)
36
SELL
News Sentiment
64
BULLISH
Revolution Medicines announced that its proprietary oncology platform has achieved a breakthrough that establishes a new standard of care for one of the most lethal cancers, a milestone that could redefine treatment protocols and expand the company’s pipeline. This development signals that the company’s platform is capable of tackling difficult‑to‑treat malignancies, potentially accelerating future approvals and opening partnership opportunities with larger oncology players. As a result, the company’s valuation prospects may improve, positioning it as a more attractive investment relative to peers in the oncology space. The breakthrough also suggests that Revolution could capture a larger share of the oncology market, which would increase its revenue potential over the next 1–10 trading days as clinical data and regulatory submissions progress. Investors should monitor the company’s upcoming regulatory filings and any partnership announcements that could validate the commercial viability of the new therapy. Additionally, watch for updates on the clinical trial timelines and any data that could confirm the efficacy and safety profile of the treatment. Finally, keep an eye on broader oncology market dynamics, as shifts in payer coverage or competitor launches could influence the company’s market share trajectory.
Earnings Summary
Revolution Medicines is a clinical‑stage oncology company headquartered in Redwood City, California, focused on developing targeted therapies for RAS‑driven cancers. The company’s pipeline includes Phase 1 RAS(ON) inhibitors such as daraxonrasib (RASONQUE) and elironrasib, as well as Phase 2 companion inhibitors like RMC‑4630, positioning it within the high‑growth biotechnology sector that targets precision oncology. In Q4 2024, the company reported an EPS of –$1.12 versus an estimate of –$0.96, a slight miss that reflects ongoing clinical development costs and the absence of revenue from product launches. The Q2 2026 earnings showed an EPS of –$2.34 against an estimate of –$2.02, again a miss, while revenue remained flat at $0, consistent with the company’s pre‑commercial status. The Q3 2026 EPS is not yet reported, but revenue guidance of $19.3 million is expected, indicating a modest acceleration in forecasted cash‑flow generation. Across the last four quarters, the company has consistently missed EPS estimates, but the trend in revenue guidance shows a gradual upward trajectory, suggesting that commercial milestones may soon materialize. Historically, RVMD’s YoY growth has been driven by pipeline progress rather than earnings, with notable beats in R&D milestones and regulatory approvals; however, earnings have remained negative as the company invests heavily in clinical trials. Recent news highlights a significant regulatory boost: the FDA granted Breakthrough Therapy Designation to RASONQUE in combination with chemotherapy for first‑line metastatic pancreatic cancer, a development that could accelerate market entry and improve investor sentiment. The insider sale by Chief Global Commercialization Officer Anthony Mancini, while sizable, has not yet triggered broader market moves and should be monitored for potential shifts in confidence. Investors should watch for the next earnings release to see whether the company can translate regulatory milestones into revenue guidance updates, and pay close attention to any FDA communications regarding accelerated review timelines, as these will be key to assessing the company’s path to commercial viability.

EPS

EstBeatMiss
$-2.65$-2.17$-1.70$-1.22$-0.74Q4'24Q2'26Q3'26
QtrEstActual+/−
Q3'26$-2.43 - -
Q2'26$-2.02$-2.34-16.0%
Q4'24$-0.96$-1.12-16.1%

Revenue

EstBeatMiss
$-3M$3M$10M$16M$22MQ4'24Q2'26Q3'26
QtrEstActual+/−
Q3'26$19M - -
Q2'26$17M$0-100.0%
Q4'24 - $0 -

Market Data

RVMD Stock Snapshot

HOLD36/100
$190.52$0.44 (0.2%)
Market cap
40.93B
Day range
$188.18 – $197.12
News sentiment
64/100 · Bullish
Analyst target
$251.21 (+31.9%)
Consensus
Buy · 30 analysts
52-week range+356.9% off low · -15.3% from high
$41.70$225.01
Price $190.52 DailyIQ Est. $268.06

The setup on Revolution Medicines, Inc. is patient: consolidation, not accumulation or distribution. The stock is liquid enough that positioning changes get absorbed without distorting the trend.

Behaviour On Record

What RVMD's own history says about today's numbers

Realized volatility (21d)
34.5% 9th pct
Below its peak
-13.9%
vs 200-day average
+36.8%
Up days (1y)
57%

Revolution Medicines, Inc. is currently running 34.5% annualised volatility over the last 21 sessions. Measured against RVMD's own 6 years of daily returns rather than a market-wide average, that is the 9th percentile unusually subdued by its own history, against a typical reading of 55.7%. The distinction matters because a number that looks calm for one stock is turbulent for another, and the absolute figure on its own tells you neither.

RVMD is trading -13.9% below its running peak. Across 6 full years on file, its median worst-drawdown-in-a-year was -44.2%, and the deepest was -55.9% in 2021. The current pullback is therefore shallower than what this stock gives back in a typical year, which is context worth having before treating it as a dislocation.

Price sits +36.8% from its 200-day moving average. Against every other day in its history, that gap ranks at the 80th percentile a wider gap than this stock usually carries. Over the past year RVMD closed higher on 57% of sessions, and it is currently 1 session into a falling streak.

On September specifically: over 7 years of records, RVMD finished the month higher 3 of 7 times, with a median return of -6.7% and an average of +1.3%. Its strongest month historically has been November at +16.1% on average, its weakest May at -2.2%. Seasonality is a weak signal on its own — a decade is a small sample and regimes change — but it is a real distribution rather than a rule of thumb.

Overnight risk is measurable too: RVMD has opened more than 2% away from the prior close in 268 of 1,657 sessions (16.2% of the time), with the largest gaps running +24.8% and -20.5%. For anyone holding through an event, that rate is a better guide to overnight exposure than the intraday range.

All figures computed from 1,658 daily closes between 2020-02-13 and 2026-09-18, split-adjusted, recomputed daily. Percentiles are against RVMD's own 7-year history, not a peer group or index.

Sector Rotation

Is money rotating into or out of RVMD's sector?

Revolution Medicines, Inc. sits in the Health Care sector, currently ranked 4th of 11 GICS sectors by relative-strength rotation score (improving).

Sector rank
#4 of 11
Sector state
Improving
Sector rotation score
100

Options Market

What is the options market pricing for RVMD?

CallsPuts

For Revolution Medicines, Inc.'s nearest expiry (2026-10-16, 26 days out), open interest is call-heavy, a bullish tilt (put/call ratio of 0.45), with at-the-money implied volatility around 44.0%. The options market is pricing roughly a ±11.7% move by that expiry — a range of about $180.84–$228.86.

Put/call ratio (2026-10-16)
0.45
ATM implied volatility
44.0%
Total open interest
3,812
Expected move by 2026-10-16
±11.7% ($180.84–$228.86)

Analyst Rating Changes

Are analysts turning bullish or bearish on RVMD?

Morgan Stanley most recently initiated coverage on Revolution Medicines, Inc. to Overweight on Sep 10, 2026 with a price target of $255. Over the last 90 days, coverage has run 0 upgrades against 0 downgrades, a net mixed lean.

Latest action
Morgan StanleyOverweight
90-day upgrades
0
90-day downgrades
0
Net rating momentum
0
DateFirmActionRatingPrice target
Sep 10, 2026Morgan StanleyInitiatedOverweight$255
Sep 9, 2026StifelMaintainedBuy$215 → $230
Aug 31, 2026NeedhamMaintainedBuy$240 → $275
Aug 28, 2026UBSMaintainedBuy$220 → $265
Aug 28, 2026GuggenheimMaintainedBuy$240 → $275
Aug 27, 2026OppenheimerMaintainedOutperform$230 → $260
Aug 27, 2026RBC CapitalMaintainedOutperform$203 → $251
Aug 27, 2026WedbushMaintainedOutperform$201 → $225
Aug 27, 2026Truist SecuritiesMaintainedBuy$231 → $239
Aug 27, 2026Evercore ISI GroupMaintainedOutperform$230 → $320
Aug 27, 2026HC Wainwright & Co.MaintainedBuy$195 → $280
Aug 21, 2026BernsteinMaintainedMarket Perform$151 → $179

RVMD Competitive Positioning

Revolution Medicines, Inc. (RVMD) is tracked alongside these names in Biotechnology on DailyIQ — ranked by market cap, with today's move alongside.